ABSTRACT
Plasma cell granuloma is a rare non-neoplastic lesion that occurs most often in the lungs, but it is not commonly seen in the maxillofacial region. Its etiology, biological behavior, ideal treatment and prognosis are still unclear and rather controversial. Very few cases of intraoral plasma cell granulomas have been reported in the past. Hence, we present an unusual case of plasma cell granuloma in a 60year-old female which was presented clinically as ill-defined swelling over left upper buccal vestibule region extending to the midpalate. Histological examination revealed fibro-cellular connective tissue stroma with inflammatory cell infiltrate containing plasma cells and lymphocytes. The plasma cells are abundant varying in size and shape, with very few large and binucleated plasma cells. Both clinically and histopathologically, it may be misinterpreted as various pathological entities thus proper evaluation of patient and histopathological examination of the tissue to rule out other lesions is mandatory.